Blaze™ SOFTWARE

Advanced ligand-based virtual screening to dramatically increase your wet screening hit rate at a fraction of the cost

Make efficient use of your time by routinely running a virtual screen in parallel to wet screening; a virtual screen of 10 million structures just takes a few hours

Blaze has been delivering lead-like hits to our customers for almost 20 years; they have achieved hit rates as high as 30%, but what they really value is the diversity of hits returned from every Blaze screen

Carry out biologically relevant virtual screens of large chemical databases
Use the electrostatic character and shape of known ligands to rapidly search large chemical collections for molecules with similar properties
Increase the diversity of your project’s leads and back-ups
Jump into new areas of chemical space
Find novel lead-like hits from known actives
Replace peptides with non-peptides or steroids with non-steroids
Achieve substantial improvements in the properties of your hits
Search algorithm increases search speed fourfold

Flexible deployment

Install Blaze on your CPU or GPU Linux clusters
Deploy our Amazon-ready version of Blaze
Access Blaze Cloud on Cresset hardware via a secure web portal
All commands are accessible through a web-based GUI, or thorugh a RESTful web service API
Blaze virtual screens can also be accessed through workflow tools such as KNIME or Pipeline Pilot
Engage Cresset Discovery to carry out a virtual screening project